Introducing the AccuLNP
Transfection Kit
AccuLNP Kit: Efficient nucleic acid transfection with low toxicity, easy to operate, and widely applicable.
AccuLNP Transfection
Reagent Kit
  • 01
    Powered by next-generation LNP delivery technology
  • 02
    Exceptional transfection efficiency for reliable results
  • 03
    Proven safety for both in vitro and in vivo applications
  • 04
    Rapid and hassle-free - encapsulation in just 60 seconds
AccuLNP In-Vitro Transfection Reagent Kit
AccuLNP In-Vivo Transfection Reagent Kit
The AccuLNP Transfection Reagent Kit harnesses cutting-edge lipid nanoparticle (LNP) technology, engineered specifically for mRNA applications. Designed for researchers who demand precision and efficiency, AccuLNP offers unparalleled performance in both in vitro and in vivo experiments.
Key Features
  • 01
    Advanced LNP Technology
    Simplifies the
    transfection process,
    delivering mRNA with
    greater efficiency and
    reliability than
    traditional vectors.
  • 02
    Universal RNA Compatibility
    Effectively
    encapsulates all RNA
    types, regardless of
    sequence or cargo size.
  • 03
    Rapid Encapsulation
    Achieve complete RNA
    encapsulation in as
    little as 60 seconds -
    no specialized
    equipment required.
  • 04
    Safe &
    Effective
    Available for both in
    vitro and in vivo use,
    with low cytotoxicity
    and minimal immunogenic
    response for maximum
    safety.

Practical Applications for Cutting-Edge Research

AccuLNP is designed to meet the diverse needs of researchers across various fields. Whether you’re developing novel mRNA therapies, advancing gene editing, or conducting fundamental research, AccuLNP provides the flexibility and reliability necessary for success.

Efficient Transfection Across Diverse Cell Lines

A total of 150 ng of GFP mRNA, encapsulated using our AccuLNP Transfection Reagent, was delivered into HEK293, Hep3B, and MCF7 cells cultured in a 96-well plate. At 24 hours post-transfection, cells were stained with DAPI and visualized under a fluorescence microscope. The results demonstrate that the AccuLNP Transfection Reagent is highly effective across a diverse range of cell types.

Superior Performance Compared to Competitors

HEK293 cells in a 96-well plate were transfected with 150 ng of GFP mRNA encapsulated using either our AccuLNP Transfection Reagent or a leading competitor’s transfection kit. At 24 hours post-transfection, cells were stained with DAPI and examined using fluorescence microscopy. The results clearly show that the AccuLNP Transfection Reagent outperforms competing transfection reagents in efficiency and effectiveness.

In Vitro Transfection with Firefly Luciferase mRNA

In addition to GFP mRNA, AccuLNP also demonstrates exceptional transfection efficiency with firefly luciferase (FLuc) mRNA in vitro. In this experiment, 500 ng of FLuc mRNA was encapsulated using the AccuLNP Transfection Reagent and transfected into HEK293 cells cultured in a 24-well plate. The cells were assessed at 24 hours post-transfection for luciferase expression using a luminescence assay, with results normalized to the competitor’s transfection efficiency.

The results clearly show that AccuLNP delivers superior efficiency in FLuc mRNA transfection, highlighting its versatility and performance across different mRNA applications.

In Vivo Transfection with Firefly Luciferase mRNA

AccuLNP is available in two formulations: one optimized for in vitro use and another specifically designed for in vivo applications. The following data show the results of an in vivo experiment using the AccuLNP in vivo version to deliver firefly luciferase (FLuc) mRNA.

For this experiment, 0.2 mg/kg of FLuc mRNA was administered via intravenous injection using the in vivo version of the AccuLNP Transfection Reagent. Luciferase expression was measured at a single time point following injection to assess transfection efficiency.